| Cultivar | Scab | Fire Blight | Powdery Mildew | Rusts1 |
| Ambrosia | VS | S | R | S |
| Belmac | R | — | T | R |
| Braeburn | S | VS | S | S |
| Cameo | S | S | R | S |
| Cortland | VS | S | S | S |
| Crimson Crisp | VR | T | T | S |
| Delicious (Red) | S | R | T | VR |
| Delicious (Golden) | S | S | VS | S |
| Dayton | VR | R | T | T |
| Early McIntosh | S | R | T | R |
| Empire | VS | R | S | R |
| Enterprise | VR | R | S | R |
| Freedom | VR | VR | R | R |
| Fuji | S | VS | R | varied |
| Gala | VS | VS | S | varied |
| Ginger Gold | VS | VS | S | VS |
| GoldRush | VR | T | S | S |
| Gravenstein | S | S | VS | varied |
| Honeycrisp | T | R | S | S |
| SIdared | S | VS | S | VS |
| Jerseymac | VS | S | S | VR |
| Jonagold | S | VS | S | R |
| Jonamac | S | S | S | R |
| Jonathan | S | VS | VS | S |
| Liberty | VR | R | R | VR |
| Lodi | S | VS | R | S |
| Macoun | VS | S | T | R |
| McIntosh | VS | S | T | VR |
| Mutsu (Crispin) | VS | VS | S | S |
| Northern Spy | S | S | S | S |
| Novamac | VR | VR | VR | VR |
| Nova Spy | R | — | S | MR |
| Paulared | R | VS | T | R |
| Pink Lady | VS | VS | R | R |
| Pristine | VR | R | R | S |
| Silken | VS | VS | S | VS |
| Stayman | VS | S | VS | S |
| Wealthy | S | S | S | VS |
| Zestar! | S | S | R | S |
VS = Very susceptible. S = Susceptible. T = Tolerant (moderately resistant under ideal conditions). R = Resistant. VR = Very resistant. — = Indicates information is not available.
1 Rusts include cedar-apple rust and quince rust. Resistance in a cultivar may vary depending on type of rust.
Adapted from Beckerman, J. (2006). Disease Susceptibility of Common Apple Cultivars. Purdue Extension BP-132-W and Cline, J., Warner, J. Wilson, K. & Zandstra, J. (1998). Disease-Resistant Apple Cultivars. Ontario Ministry of Agriculture, Food & Rural Affairs, Factsheet 98-013.